Gene information
Official symbol VTN
Official full name vitronectin
Gene type protein-coding gene
Chromosome17q11.2
Alias symbolVN
Gene familyReceptor ligands; Complement system regulators and receptors
Resources
Entrez Gene 7448
HGNC HGNC:12724
Ensembl ENSG00000109072
Vega OTTHUMG00000132500
UCSC uc002hbc.4
GO terms: 61 records
GO Description Category LogP Number of genes Detail
GO:0001704 formation of primary germ layer GO Biological Processes -8.70692533 22 More
GO:0001706 endoderm formation GO Biological Processes -7.82381493 14 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0005044 scavenger receptor activity GO Molecular Functions -5.60384289 7 More
GO:0005178 integrin binding GO Molecular Functions -20.5409412 26 More
GO:0005198 structural molecule activity GO Molecular Functions -7.51921139 30 More
GO:0005201 extracellular matrix structural constituent GO Molecular Functions -12.8379048 20 More
GO:0005539 glycosaminoglycan binding GO Molecular Functions -36.7680176 44 More
GO:0007160 cell-matrix adhesion GO Biological Processes -9.58867374 15 More
GO:0007369 gastrulation GO Biological Processes -9.78060849 28 More
GO:0007492 endoderm development GO Biological Processes -8.07123392 17 More
GO:0008201 heparin binding GO Molecular Functions -33.5542939 37 More
GO:0010466 negative regulation of peptidase activity GO Biological Processes -24.1438543 35 More
GO:0010951 negative regulation of endopeptidase activity GO Biological Processes -24.7873219 35 More
GO:0014910 regulation of smooth muscle cell migration GO Biological Processes -16.4082106 27 More
GO:0014911 positive regulation of smooth muscle cell migration GO Biological Processes -11.1068742 16 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0030193 regulation of blood coagulation GO Biological Processes -37.6853179 30 More
GO:0030194 positive regulation of blood coagulation GO Biological Processes -18.9359595 14 More
GO:0030195 negative regulation of blood coagulation GO Biological Processes -29.1940441 22 More
GO:0030246 carbohydrate binding GO Molecular Functions -4.83003123 14 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031589 cell-substrate adhesion GO Biological Processes -10.7590108 32 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0035987 endodermal cell differentiation GO Biological Processes -8.15231722 13 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0045861 negative regulation of proteolysis GO Biological Processes -27.9905009 43 More
GO:0048260 positive regulation of receptor-mediated endocytosis GO Biological Processes -10.1090317 11 More
GO:0048598 embryonic morphogenesis GO Biological Processes -22.1253699 83 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.9747849 34 More
GO:0050818 regulation of coagulation GO Biological Processes -40.0839917 32 More
GO:0050819 negative regulation of coagulation GO Biological Processes -31.8350192 24 More
GO:0050820 positive regulation of coagulation GO Biological Processes -18.6547980 14 More
GO:0050839 cell adhesion molecule binding GO Molecular Functions -14.4506551 68 More
GO:0050840 extracellular matrix binding GO Molecular Functions -6.18341292 8 More
GO:0050878 regulation of body fluid levels GO Biological Processes -57.9546976 69 More
GO:0051099 positive regulation of binding GO Biological Processes -11.1715489 31 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051346 negative regulation of hydrolase activity GO Biological Processes -26.0030636 42 More
GO:0052547 regulation of peptidase activity GO Biological Processes -35.5643317 55 More
GO:0052548 regulation of endopeptidase activity GO Biological Processes -34.9486589 53 More
GO:0061041 regulation of wound healing GO Biological Processes -35.8633788 36 More
GO:0061045 negative regulation of wound healing GO Biological Processes -28.2986689 25 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:0072562 blood microparticle GO Cellular Components -39.0217600 39 More
GO:0090287 regulation of cellular response to growth factor stimulus GO Biological Processes -21.1381780 60 More
GO:0090303 positive regulation of wound healing GO Biological Processes -15.9447313 16 More
GO:1900046 regulation of hemostasis GO Biological Processes -39.0044157 31 More
GO:1900047 negative regulation of hemostasis GO Biological Processes -30.8008788 23 More
GO:1900048 positive regulation of hemostasis GO Biological Processes -18.9359595 14 More
GO:1901681 sulfur compound binding GO Molecular Functions -28.2504512 39 More
GO:1903034 regulation of response to wounding GO Biological Processes -34.9293555 38 More
GO:1903035 negative regulation of response to wounding GO Biological Processes -27.3379640 26 More
GO:1903036 positive regulation of response to wounding GO Biological Processes -14.4451296 16 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
KEGG pathways: 6 records
KEGG Description Category LogP Number of genes Detail
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa04510 Focal adhesion KEGG Pathway -16.5268196 41 More
hsa04512 ECM-receptor interaction KEGG Pathway -16.8587083 28 More
hsa04610 Complement and coagulation cascades KEGG Pathway -50.1154932 39 More
hsa05165 Human papillomavirus infection KEGG Pathway -8.63301470 40 More
hsa05205 Proteoglycans in cancer KEGG Pathway -18.5545131 27 More
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
vitronectin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Aslan S et al. Herz. 2015
vitronectin proteomics major adverse cardiovascular events[prognosis (bad)] acute myocardial infarction Aslan S et al. Herz. 2015
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